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LABORATORIOS SAVAL

Contribution in Chile

Infectology, Ophthalmology, Immunology and Oncology, Gastroenterology, Bronchopulmonar, Cardiology, Rheumatology, Psychiatry.

Infectology

  • First Sulfas and first Penicillins
  • First semisynthetic Penicillins (Ampicillin, Cloxacillin, Amoxicillin, etc)
  • First antiviral agent for systemic use (Acyclovir)
  • First medicine world-wide approved for the etiological treatment of AIDS (Zidovudine)

Ophthalmology

  • Introduction of the first ophthalmic corticoid
  • Introduction of the first ophthalmic anti-viral
  • Introduction of ophthalmic Adrenergic-B antagonist

Immunology and Oncology

  • First immunodepressant useful in organs transplant.

Gastroenterology

  • Introduction of the H2 Antagonists (Cimetidine, Ranitidine, Famotidine)
  • Introduction of the first prokinetics (Metoclopramide, Domperidone, Cisapride)
  • First proton pump inhibitor (Omeprazole)

Bronchopulmonar

  • First sustained release theophylline made in Chile

Cardiology

  • Introduction and development in Chile of ACE Inhibitors
  • Introduction of the first statin for cholesterol control
  • Introduction of Angiotensin II blocking agents

Rheumatology

  • Introduction of first Uric acid synthesis inhibitor (Allopurinol).
  • Introduction of Naproxen in Chile (Gold-standard in the NSAID's therapy).

Psychiatry

  • Wide range of Benzodiazepines (from Chlordiazepoxide to Clonazepam)
  • Introduction of the first non-benzodiazepinic ansyolitic (Buspirone)
  • First specific serotoninergic antidepressant (Fluoxetine).
  • Innovative non-benzodiazepine hypnotic agent (Zolpidem).