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AMOVAL

Antibiotic therapy


Pharmacological Properties:
Amoxicillin is a broad-spectrum aminopenicillin, structurally related to ampicillin. Stable in acidic media and it is completely absorbed from the gastrointestinal tract, not being affected by the presence of food.
Indications:
Acute and chronic bronchitis; acute pharyngitis and tonsillitis; sinusitis; otitis media; urinary infection; shigellosis; meningitis; septicemia. AMOVAL 1g is also indicated in patients on acid suppression therapy (with omeprazole) and when it is combined with another antibiotic (claritromicine) to eradicate Helicobacter pylori (triple therapy).
Dosage and Administration:
Respiratory infections, recommended dosage: Adults: one 500 or 750mg tablet three times daily or 1 g every 12 hours. Children: 20 to 40mg/kg/day divided in three doses (1⁄2 to 1 tea spoon 250 or 500mg suspension based on weight, every 8 hours). In drug-resistant Streptococcus pneumoniae 80 - 90mg/Kg/day divided in two or three doses (every 8 to 12 hours). Usual dosage to eradicate Helicobacter pylori. 1g every 12 hours under triple therapy with omeprazole and claritromicine for 7 days.
Contraindications:
Hypersensitivity to penicillin and its derivatives.
Precautions and Warnings:
Allergic reactions to penicillins should be ruled out before administering AMOVAL. Renal function should be assessed periodically in patients with renal impairment on long term treatments.
Adverse Reactions:
Allergic reactions characterized by cutaneous rash, oral lesions and anaphylactic shock, the most severe form of allergic reaction, may occur
Interactions:
Interaction with allopurinol has been reported.
On-dosages:
Besides the aforementioned side effects, no toxic effect caused by amoxicillin overdose has been reported.
Storage:
Store below 30°C, away form light and moist.


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