LABORATORIOS SAVAL

Infectology

• First Sulfas and first Penicillins
• First semisynthetic Penicillins (Ampicillin, Cloxacillin, Amoxicillin, etc)
• First antiviral agent for systemic use (Acyclovir)
• First medicine world-wide approved for the etiological treatment of AIDS (Zidovudine)

Ophthalmology

• Introduction of the first ophthalmic corticoid
• Introduction of the first ophthalmic anti-viral
• Introduction of ophthalmic Adrenergic-B antagonist

Immunology and Oncology

• First immunodepressant useful in organs transplant.

Gastroenterology

• Introduction of the H2 Antagonists (Cimetidine, Ranitidine, Famotidine)
• Introduction of the first prokinetics (Metoclopramide, Domperidone, Cisapride)
• First proton pump inhibitor (Omeprazole)

Bronchopulmonar

• First sustained release theophylline made in Chile

Cardiology

• Introduction and development in Chile of ACE Inhibitors
• Introduction of the first statin for cholesterol control
• Introduction of Angiotensin II blocking agents

Rheumatology

• Introduction of first Uric acid synthesis inhibitor (Allopurinol).
• Introduction of Naproxen in Chile (Gold-standard in the NSAID's therapy).

Psychiatry

• Wide range of Benzodiazepines (from Chlordiazepoxide to Clonazepam)
• Introduction of the first non-benzodiazepinic ansyolitic (Buspirone)
• First specific serotoninergic antidepressant (Fluoxetine).
• Innovative non-benzodiazepine hypnotic agent (Zolpidem).