Contribution in Chile
Infectology, Ophthalmology, Immunology and Oncology, Gastroenterology, Bronchopulmonar, Cardiology, Rheumatology, Psychiatry.
Infectology
- First Sulfas and first Penicillins
- First semisynthetic Penicillins (Ampicillin, Cloxacillin, Amoxicillin, etc)
- First antiviral agent for systemic use (Acyclovir)
- First medicine world-wide approved for the etiological treatment of AIDS (Zidovudine)
Ophthalmology
- Introduction of the first ophthalmic corticoid
- Introduction of the first ophthalmic anti-viral
- Introduction of ophthalmic Adrenergic-B antagonist
Immunology and Oncology
- First immunodepressant useful in organs transplant.
Gastroenterology
- Introduction of the H2 Antagonists (Cimetidine, Ranitidine, Famotidine)
- Introduction of the first prokinetics (Metoclopramide, Domperidone, Cisapride)
- First proton pump inhibitor (Omeprazole)
Bronchopulmonar
- First sustained release theophylline made in Chile
Cardiology
- Introduction and development in Chile of ACE Inhibitors
- Introduction of the first statin for cholesterol control
- Introduction of Angiotensin II blocking agents
Rheumatology
- Introduction of first Uric acid synthesis inhibitor (Allopurinol).
- Introduction of Naproxen in Chile (Gold-standard in the NSAID's therapy).
Psychiatry
- Wide range of Benzodiazepines (from Chlordiazepoxide to Clonazepam)
- Introduction of the first non-benzodiazepinic ansyolitic (Buspirone)
- First specific serotoninergic antidepressant (Fluoxetine).
- Innovative non-benzodiazepine hypnotic agent (Zolpidem).